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Flow Visualization and Characterization of an Artery Model with Stenosis

Shuib, Anis (2011) Flow Visualization and Characterization of an Artery Model with Stenosis. [Citation Index Journal]

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Abstract

Cardiovascular diseases, principally atherosclerosis, are responsible for 30% of world deaths. Atherosclerosis is due to the formation of plaque. The fatty plaque may be at risk of rupture, leading typically to stroke and heart attack. The plaque is usually associated with a high degree of lumen reduction, called a stenosis.It is increasingly recognized that the initiation and progression of disease and the occurrence of clinical events is a complex interplay between the local biomechanical environment and the local vascular biology. The aim of this study is to investigate the flow behavior through a stenosed artery. A physical experiment was performed using an artery model and blood analogue fluid. An axisymmetric model constructed consists of contraction and expansion region that follow a mathematical form of cosine function. A 30% diameter reduction was used in this study. The flow field was measured using particle image velocimetry (PIV). Spherical particles with 20μm diameter were seeded in a water-glycerol-NaCl mixture. Steady flow Reynolds numbers are 250. The area of interest is the region after the stenosis where the flow separation occurs. The velocity field was measured and the velocity gradient was investigated. There was high particle concentration in the recirculation zone. High velocity gradient formed immediately after the stenosis throat created a lift force that enhanced particle migration to the flow separation area.

Item Type:Citation Index Journal
Subjects:T Technology > T Technology (General)
R Medicine > RZ Other systems of medicine
T Technology > TA Engineering (General). Civil engineering (General)
Departments / MOR / COE:Departments > Chemical Engineering
Research Institutes > Institute for Health Analytics
ID Code:7475
Deposited By: Anis Shuib
Deposited On:12 Mar 2012 00:14
Last Modified:19 Jan 2017 08:22

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